abstract：:Chronic hypoxia is related to many pathological conditions: aging, heart and respiratory failure, sleep apneas, smoke, chronic obstructive pulmonary disease (COPD), diabetes, hypertension and arteriosclerosis, all characterized by reductions of sleep-related erections (SREs) and by erectile dysfunction (ED). Sleep-rel...

journal_title：International journal of impotence research

authors： Verratti V,Di Giulio C,Berardinelli F,Pellicciotta M,Di Francesco S,Iantorno R,Nicolai M,Gidaro S,Tenaglia R

更新日期：2007-09-01 00:00:00

abstract：:Radical prostatectomy has been shown to have a potential negative impact on penile health. Stretched penile length (SPL), which most closely correlates with erect penile length, was significantly reduced in almost half of men undergoing surgery in several studies. The purpose of this study was to test whether early in...

journal_title：International journal of impotence research

authors： Dalkin BL,Christopher BA

更新日期：2007-09-01 00:00:00

abstract：:Fifty partial and non-responders (Clinical Global Impression-Sexual Function (CGI-SF) score>2), out of 76 men who completed a 6-week, double-blind, placebo-controlled trial of sildenafil treatment for serotonergic antidepressant-associated sexual dysfunction, were eligible for an additional 6-week trial of open-label ...

journal_title：International journal of impotence research

authors： Nurnberg HG,Fava M,Gelenberg AJ,Hensley PL,Paine S

更新日期：2007-03-01 00:00:00

abstract：:This study was conducted to determine rate and related factors of dyspareunia. Three hundred and nineteen women aged 15-49 years were surveyed. A questionnaire was used to collect data. Pelvic examinations and connective tissue disorders were investigated. At whole 54.5% had dyspareunia. The means of gravidity, parity...

journal_title：International journal of impotence research

authors： Sobhgol SS,Alizadeli Charndabee SM

更新日期：2007-01-01 00:00:00

abstract：:Erectile dysfunction (ED) is the consistent inability to achieve and maintain an erection sufficient for satisfactory sexual activity. Erectile dysfunction affects as many as 30 million men in America, with an increasing prevalence with age. Erectile dysfunction is secondary to organic, psychogenic and combined causes...

journal_title：International journal of impotence research

authors： Golijanin D,Singer E,Davis R,Bhatt S,Seftel A,Dogra V

更新日期：2007-01-01 00:00:00

abstract：:We describe a case of gunshot wound to the corpora cavernosa caused by a low-velocity bullet in a 43-year-old man. He volunteered that his lover's husband shot him with a handgun. The bullet had penetrated the right gluteal region with no exit wound causing a right corpus cavernosum lesion. A penile colour-duplex dopp...

journal_title：International journal of impotence research

authors： Giammusso B,Pomara G,Giannarini G,Motta M

更新日期：2006-11-01 00:00:00

abstract：:Several trials and reviews provide evidence for the efficacy of phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction (ED). However, little is known about the impact of treatment effect modifiers other than concomitant diseases. Our objective was to identify patient and trial characteristics as well ...

journal_title：International journal of impotence research

authors： Kriston L,Harms A,Berner MM

更新日期：2006-11-01 00:00:00

abstract：:Phosphodiesterase 5 (PDE5) inhibitors are efficacious in treating patients with erectile dysfunction. New PDE5 inhibitors with different selectivity and pharmacokinetic profiles have been vigorously pursued. Here we report two novel, potent, and selective PDE5 inhibitors, JNJ-10280205 and JNJ-10287069, with Ki values ...

journal_title：International journal of impotence research

authors： Qiu Y,Bhattacharjee S,Kraft P,Mathew John T,Haynes-Johnson D,Jiang W,Sui Z,Lundeen S

更新日期：2006-09-01 00:00:00

abstract：:Early pharmacological prophylaxis has been reported to increase the return of spontaneous erections following radical prostatectomy (RP). In this study, we evaluated the role of intracavernosal alprostadil (PGE1) combined with sildenafil in stimulating early recovery of spontaneous erections following RP. In this pros...

journal_title：International journal of impotence research

authors： Nandipati K,Raina R,Agarwal A,Zippe CD

更新日期：2006-09-01 00:00:00

abstract：:Men with the metabolic syndrome demonstrate an increased prevalence of erectile dysfunction (ED). In the present study, we tested the effect of a Mediterranean-style diet on ED in men with the metabolic syndrome. Men were identified in our database of subjects participating in controlled trials evaluating the effect o...

journal_title：International journal of impotence research

authors： Esposito K,Ciotola M,Giugliano F,De Sio M,Giugliano G,D'armiento M,Giugliano D

更新日期：2006-07-01 00:00:00

abstract：:Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) has long been used as a traditional Chinese medicine for dysfunctions of the endocrine system and inflammation conditions. However, the effect of adlay seed on the endocrine system has not yet been reported. In the present study, the effects and the mechanisms of metha...

journal_title：International journal of impotence research

authors： Hsia SM,Chiang W,Kuo YH,Wang PS

更新日期：2006-05-01 00:00:00

abstract：:Routine removal of the reservoir in explanting a malfunctioning three-piece penile implant raises debates because that the retained reservoir has little risk of erosion and it often needs a second incision to remove the reservoir. We reported a case whose retained reservoir resulted in nonbacterial inflammation around...

journal_title：International journal of impotence research

authors： Jiann BP,Ou CW,Lin JT,Huang JK

更新日期：2006-05-01 00:00:00

abstract：:The aim of this study was to report feasibility, benefit and complications of superselective transcatheter autologous clot embolizations and duplex sonography-guided compression therapy in four patients with delayed post-traumatic high-flow priapism. Medical records of four consecutive patients diagnosed with delayed ...

journal_title：International journal of impotence research

authors： Cakan M,Altu Gcaron U,Aldemir M

更新日期：2006-03-01 00:00:00

abstract：:We have investigated the reliability of intracavernosal prostaglandin E1 (PGE1) office vs self-injection therapy in patients with erectile dysfunction (ED). A total of 298 male patients with ED were enrolled in this study. In all patients, intracavernosal titration of the PGE1 dose was performed. A total of 106 patien...

journal_title：International journal of impotence research

authors： El-Sakka AI

更新日期：2006-03-01 00:00:00

abstract：:Chronic heart failure (HF) is an increasingly common cardiovascular disorder. The goal of health-care providers is to optimize quality of life in this population, including sexual health. Up to 75% of patients with HF report erectile dysfunction (ED). As HF is a condition with distinct physiologic sequelae, some uniqu...

journal_title：International journal of impotence research

authors： Rastogi S,Rodriguez JJ,Kapur V,Schwarz ER

更新日期：2005-12-01 00:00:00

abstract：:Hypercholesterolemia is a major risk factor for erectile dysfunction. To understand the mechanism(s) of hypercholesterolemia-induced erectile dysfunction, we studied the effect of lysophosphatidylcholine (LPC) on the membrane conductance of corporal smooth muscle cells. We used cultured human corporal smooth muscle ce...

journal_title：International journal of impotence research

authors： So I,Chae MR,Kim SJ,Lee SW

更新日期：2005-11-01 00:00:00

abstract：:This study examined the effects of a new phosphodiesterase type 5 inhibitor, DA-8159, on erectile function associated with hypercholesterolemia. First of all, in order to investigate whether chronic administration of DA-8159 prevents the development of erectile dysfunction associated with hypercholesterolemia, male SD...

journal_title：International journal of impotence research

authors： Kang KK,Yu JY,Yoo M,Kwon JW

更新日期：2005-09-01 00:00:00

abstract：:The first goal of this study was to examine the effect of secondhand smoking on neurogenic, endothelium- and cGMP-dependent relaxant responses of rabbit corpus cavernosum smooth muscle. Our second goal was to determine whether such an effect can be prevented by oral administration of L-arginine. Male New Zealand rabbi...

journal_title：International journal of impotence research

authors： Göçmez SS,Utkan T,Duman C,Yildiz F,Ulak G,Gacar MN,Erden F

更新日期：2005-09-01 00:00:00

abstract：:The human T-lymphotropic virus type I (HTLV-I) is a retrovirus associated with a chronic myelopathy known as HTLV-I-Associated Myelopathy or Tropical Spastic Paraparesis (HAM/TSP). The main objective was to assess the frequency of erectile dysfunction (ED) in HTLV-I-infected individuals from Salvador and other cities ...

journal_title：International journal of impotence research

authors： Castro N,Oliveira P,Freitas D,Rodrigues W,Muniz A,Carvalho E

更新日期：2005-07-01 00:00:00

abstract：:Even with the help of modern pharmacology, treatment of erectile dysfunction often remains complex, and requires taking into account the social, psychological, and behavioral dimensions of the disorder. This brief report presents a case study highlighting this complexity. ...

journal_title：International journal of impotence research

authors： Bianchi-Demicheli F,Ortigue S,De Ziegler D,Damsa C,Sekoranja L

更新日期：2005-07-01 00:00:00

abstract：:In a prospective, placebo-controlled, one group crossover design study, we tested whether adding programmed intracavernous PGE1 injections (IC-PGE1) can improve the effectiveness of sildenafil in erectile dysfunction (ED) patients unresponsive to monotherapy with this drug. In all, 40 ED patients who had experienced u...

journal_title：International journal of impotence research

authors： Gutierrez P,Hernandez P,Mas M

更新日期：2005-07-01 00:00:00

abstract：:We report a rare complication of a penile prosthesis reservoir removed from the urinary bladder in a patient with a history of radiation therapy and previous abdominal surgery. The reservoir was retrieved by open cystotomy 13 years after original placement. ...

journal_title：International journal of impotence research

authors： Brusky J,Dikranin A,Aboseif S

更新日期：2005-05-01 00:00:00

abstract：:Venous insufficiency of the corpora cavernosa is the second most common cause of erectile dysfunction (ED). A functional insufficiency of the venous system has been hypothesised, but the cause is still unclear. To evaluate a possible endocrine mechanism, we have studied hormone profile in a group of nine patients with...

journal_title：International journal of impotence research

authors： Mancini A,Milardi D,Bianchi A,Summaria V,De Marinis L

更新日期：2005-05-01 00:00:00

abstract：:This research was carried out to evaluate the prevalence of carotid and/or lower limb artery abnormalities in patients with arterial erectile dysfunction (ED). To this end, patients with ED (Andrology Unit) or suspected peripheral atherosclerosis (Angiology Unit) underwent an independent and parallel echo-Duplex exami...

journal_title：International journal of impotence research

authors： Vicari E,Arcidiacono G,Di Pino L,Signorelli S,Arancio A,Sorrentino F,Battiato C,D'Agata R,Calogero AE

更新日期：2005-05-01 00:00:00

abstract：:Only few studies have investigated the impact of surgery for rectal cancer on sexual function. Little of that research included quality of life (QoL) aspects and hardly any study analyzed the impact of age, gender and type of surgery on sexual function. The aim of the presented study was to address these issues. Over ...

journal_title：International journal of impotence research

authors： Schmidt CE,Bestmann B,Küchler T,Kremer B

更新日期：2005-05-01 00:00:00

abstract：:Tamsulosin is the most potent adrenergic alpha-1 antagonist used for the treatment of benign prostatic hyperplasia. Priapism has been reported rarely in patients taking Prazosin, Doxazosin and Terazosin. We describe an otherwise healthy man with recurrent and then persistent unresolved priapism after the use of tamsul...

journal_title：International journal of impotence research

authors： Pahuja A,Bashir J,Williamson EM,Barber N

更新日期：2005-05-01 00:00:00

abstract：:The frequency of sexual dysfunction (SD) is not very well known in patients with chronic hepatitis C. In this study, the prevalence of SD and its correlations with psychological and biological variables was assessed in 46 HCV positive patients. The mean age of patients was 46.4+/-9.4 y; the mean duration of HCV infect...

journal_title：International journal of impotence research

authors： Soykan A,Boztaş H,Idilman R,Ozel ET,Tüzün AE,Ozden A,Ozden A,Kumbasar H

更新日期：2005-03-01 00:00:00

abstract：:The effects of hypoxia (pO2: 50 mmHg), acidosis (pH: 6.9) or glucopenia (absence of glucose) in vitro on the tone of the rabbit corpus cavernosum were investigated. The recovery of smooth muscle contractility following exposure to these conditions was also assessed. Hypoxia, acidosis or glucopenia alone or in combinat...

journal_title：International journal of impotence research

authors： Muneer A,Cellek S,Dogan A,Kell PD,Ralph DJ,Minhas S

更新日期：2005-01-01 00:00:00

abstract：:This prospective study determined the rate of abandonment of sildenafil therapy and assessed the reasons for abandonment. Between January 2001 and December 2002, 234 patients with erectile dysfunction (ED) at three independent centers successfully began therapy with sildenafil 50 or 100 mg. The rate of noncompliance w...

journal_title：International journal of impotence research

authors： Klotz T,Mathers M,Klotz R,Sommer F

更新日期：2005-01-01 00:00:00

abstract：:Sildenafil citrate, marketed as Viagra, for the treatment of erectile dysfunction, has a proven record of safety in humans as predicted by the results of extensive pharmacological and toxicological testing in animals and in vitro, and confirmed by pharmacokinetic exposure data. The aim of this paper is to review succi...

journal_title：International journal of impotence research

authors： Abbott D,Comby P,Charuel C,Graepel P,Hanton G,Leblanc B,Lodola A,Longeart L,Paulus G,Peters C,Stadler J

更新日期：2004-12-01 00:00:00

abstract：:We estimated the incidence of erectile dysfunction (ED) in a population-based sample during 5-y follow-up and determined how the rate was affected by sociodemographic and life-style factors. The target population comprised all men aged 50, 60 or 70 y residing in the city of Tampere or 11 surrounding municipalities in ...

journal_title：International journal of impotence research

authors： Shiri R,Koskimäki J,Hakama M,Häkkinen J,Huhtala H,Tammela TL,Auvinen A

更新日期：2004-10-01 00:00:00

abstract：:Erectile dysfunction (ED) can be an early and first sign of an underlying systemic disease. A screening program is offered by the Israeli Defense Force for career servicemen at the staff periodic examination center (SPEC), the aim of which was early detection of morbidity. We introduced the Sexual Human Inventory for ...

journal_title：International journal of impotence research

authors： Heruti RJ,Yossef M,Shochat T

更新日期：2004-08-01 00:00:00

abstract：:The association between erectile dysfunction (ED) and acute myocardial infarction (AMI) among men was examined in the Integrated Healthcare Information Services National Managed Care Benchmark Database (IHCIS). The IHCIS is a fully de-identified, HIPAA-compliant database and includes complete medical history for more ...

journal_title：International journal of impotence research

authors： Blumentals WA,Gomez-Caminero A,Joo S,Vannappagari V

更新日期：2004-08-01 00:00:00

abstract：:Nitric oxide (NO) is a physiologic signal essential to penile erection, and disorders that reduce NO synthesis or release in the erectile tissue are commonly associated with erectile dysfunction. NO synthase (NOS) catalyzes production of NO from L-arginine. While both constitutively expressed neuronal NOS (nNOS) and e...

journal_title：International journal of impotence research

authors： Burnett AL

更新日期：2004-06-01 00:00:00

abstract：:Phosphodiesterase type 5 (PDE5) inhibitors have reduced efficacy in treating erectile dysfunction (ED) in conditions where there is a lack of endogenous nitric oxide (NO). Therefore, NO-releasing PDE5 inhibitors have been developed. Here we report the effect of such a compound, NCX-911, on the tone and nitrergic relax...

journal_title：International journal of impotence research

authors： Kalsi JS,Kell PD,Cellek S,Ralph DJ

更新日期：2004-04-01 00:00:00

abstract：:Penile implant malfunction is usually treated by removal of the original malfunctioning implant followed by replacement with a new device. During replacement, the original implant can be explanted without any difficulty, as it is not adherent to the surrounding tissue. Herein, we describe two cases of tissue ingrowth ...

journal_title：International journal of impotence research

authors： Rajpurkar A,Shah R,Starkman J,Dhabuwala CB

更新日期：2004-04-01 00:00:00

abstract：:Peyronie's disease is a localized connective tissue disorder, caused by trauma to the erect penis, which results in cellular proliferation and excess extracellular matrix production within the tunica albuginea of the penis. We have previously demonstrated that cells derived from Peyronie's disease plaque tissue demons...

journal_title：International journal of impotence research

authors： Mulhall JP,Martin DJ,Lubrano T,Moser M,Kwon E,Wojcik E,Shankey TV

更新日期：2004-04-01 00:00:00

abstract：:The role of steroid hormones in regulating vaginal smooth muscle contractility was investigated. Rabbits were kept intact or ovariectomized. After 2 weeks, animals were continuously infused with vehicle or supraphysiological levels of testosterone (100 microg/day), or estradiol (200 microg/day), for an additional 2 we...

journal_title：International journal of impotence research

authors： Kim NN,Min K,Pessina MA,Munarriz R,Goldstein I,Traish AM

更新日期：2004-02-01 00:00:00

abstract：:Gynecomastia is an unusual side effect associated with testosterone replacement therapy (TRT) that has been traditionally treated with surgery, radiation, or discontinuation of testosterone supplementation. We report here our experience with two cases of gynecomastia in men undergoing TRT who were successfully treated...

journal_title：International journal of impotence research

authors： Rhoden EL,Morgentaler A

更新日期：2004-02-01 00:00:00

abstract：:The imbalance between vasoconstrictors and vasodilators may play an important role in the pathogenesis of erectile dysfunction (ED). A total of 36 patients with ED, organogenic [diabetic (n=12) and nondiabetic (n=12)] and psychogenic (n=12) etiology, and 12 healthy adult men as controls were included. The levels of en...

journal_title：International journal of impotence research

authors： Hamed EA,Meki AR,Gaafar AA,Hamed SA

更新日期：2003-12-01 00:00:00